Manuscript Details

Source

Eckenrode, J., Campa, M., Luckey, D. W., Henderson, C. R., Cole, R., Kitzman, H., Anson, E., Sidora-Arcoleo, K., Powers, J., & Olds, D. (2010). Long-term effects of prenatal and infancy nurse home visitation on the life course of youths: 19-year follow-up of a randomized trial. Archives of Pediatrics & Adolescent Medicine, 164(1), 9-15.

High rating
Study reviewed under: Handbook of Procedures and Standards, Version 1

Note: Navigate to model page for more information about the home visiting model. See the study manuscript for more information about how the model was implemented in this study.

Author Affiliation

David L. Olds, a study author, is a developer of this model.

Funding Sources

This research was supported by grant 801-099 from the Smith Richardson Foundation. Support for earlier phases of this trial was provided by a Senior Research Scientist Award (Dr Olds) and by grants from the Prevention Research and Behavioral Medicine Branch of the National Institute of Mental Health, the Assistant Secretary for Planning and Evaluation, Health and Human Services, the Bureau of Maternal and Child Health (Department of Health and Human Services), the Robert Wood Johnson Foundation, the W.T. Grant Foundation, the Ford Foundation, and the Commonwealth Fund. Dr Olds’ Research Center at the University of Colorado has a contract with the NFP National Service Office to conduct research on improving the NFP model.

Study Design

Design Attrition Baseline equivalence Confounding factors Valid, reliable measures?
Randomized controlled trial Low

Established on SES; Not established on maternal race, but analysis controlled for child race.

None

Not assessed in manuscripts reviewed under Handbook of Procedures and Standards, Version 1
Notes

In 2020, HomVEE updated this review to move the 14 findings related to the child's sexual behavior, pregnancy, and use of alcohol or drugs from the Child Health domain to the Child Development and School Readiness domain because ACF determined that all measures of child behavioral health, including children's risky behaviors, belong in HomVEE's Child Development and School Readiness domain.

Study Participants

The authors actively recruited pregnant, first-time mothers who were fewer than 25 weeks pregnant, were younger than 19 years old, were single parents, or had low socioeconomic status. Between April 1978 and September 1980, 500 women were interviewed and 400 were randomly assigned to one of four conditions (two treatment and two comparison groups). This study measured the sample when the children were 19 years old. The sample included 310 youth (170 in the treatment groups and 140 in the comparison groups).

Setting

Elmira, NY

Home Visiting Services

The study included two treatment groups. Families in the first treatment group were provided nurse home visits through the mother’s pregnancy, sensory and developmental screening for the child at 12 and 24 months of age, referrals for clinical evaluation and treatment, and free transportation for prenatal and well-child care through the child’s second birthday. Families in the second treatment group were provided the same services as the first treatment group except that the nurse continued visits through the child’s second birthday.

Note: Navigate to model page for more information about the home visiting model. See the study manuscript for more information about how the model was implemented in this study.

Comparison Conditions

The study included two comparison groups, which were combined for the analyses. Families in the first group were provided the same sensory and developmental screening for the child at 12 and 24 months of age as the treatment groups. Based on the results of these screenings, the children were referred for clinical evaluation and treatment when needed. Families in the second group were provided these same screening services plus free transportation for prenatal and well-child care through the child’s second birthday. There were no differences between in the groups in their use of prenatal and well-child care.

Were any subgroups examined?
Yes
Subgroups examined

• Child gender (boy or girl) • Subgroups defined by combinations of maternal characteristics (unmarried and low income)

Findings that rate moderate or high in this manuscript

Child development and school readiness
Outcome measure Timing of follow-up Rating Direction of Effect Effect size (absolute value) Stastical significance Sample size Sample description

Ever been pregnant/made a girl pregnant

19-year follow-up

High
0.02

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy + infancy and comparison (Elmira)

Ever fathered a child/given birth

19-year follow-up

High
0.02

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy + infancy and comparison (Elmira)

Number of sex partners, past year

19-year follow-up

High

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy + infancy and comparison (Elmira)

Frequency of birth control use

19-year follow-up

High

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy + infancy and comparison (Elmira)

Frequency of condom use

19-year follow-up

High

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy + infancy and comparison (Elmira)

Ever been pregnant/made a girl pregnant

19-year follow-up

High
0.04

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Ever fathered a child/given birth

19-year follow-up

High
0.10

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Number of sex partners, past year

19-year follow-up

High

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Frequency of birth control use

19-year follow-up

High

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Frequency of condom use

19-year follow-up

High

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Graduated from high school

19-year follow-up

High
0.12

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Graduated from high school

19-year follow-up

High
0.25

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Illicit drug use

19-year follow-up

High
0.08

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Binge drinking

19-year follow-up

High
0.10

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Illicit drug use

19-year follow-up

High
0.02

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Binge drinking

19-year follow-up

High
0.11

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Subgroups
Outcome measure Timing of follow-up Rating Direction of Effect Effect size (absolute value) Stastical significance Sample size Sample description

Illicit drug use

19-year follow up

High
0.11

Not statistically significant, p = 0.65

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Binge drinking

19-year follow up

High
0.12

Not statistically significant, p = 0.67

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Graduated from high school

19-year follow up

High
0.30

Not statistically significant, p = 0.29

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Ever been pregnant

19-year follow up

High
0.02

Not statistically significant, p = 0.93

116 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Ever given birth

19-year follow up

High
0.05

Not statistically significant, p = 0.86

116 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Number of sex partners, past year

19-year follow up

High
0.00

Not statistically significant, p = 1.00

115 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Effect rating key
Favorable finding / Statistically significant
Unfavorable finding / Statistically significant
Ambiguous finding / Statistically significant
No effect / Not statistically significant
Family economic self-sufficiency
Outcome measure Timing of follow-up Rating Direction of Effect Effect size (absolute value) Stastical significance Sample size Sample description

Economically productive

19-year follow-up

High
0.09

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Ever used AFDC

19-year follow-up

High
0.26

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Ever used food stamps

19-year follow-up

High
0.02

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Ever used Medicaid

19-year follow-up

High
0.06

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Economically productive

19-year follow-up

High
0.13

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Ever used AFDC

19-year follow-up

High
0.68

Statistically significant, p < 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Ever used food stamps

19-year follow-up

High
0.06

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Ever used Medicaid

19-year follow-up

High
0.34

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Subgroups
Outcome measure Timing of follow-up Rating Direction of Effect Effect size (absolute value) Stastical significance Sample size Sample description

Economically productive

19-year follow up

High
0.17

Not statistically significant, p = 0.38

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Ever used AFDC

19-year follow up

High
0.35

Not statistically significant, p = 0.32

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Ever used food stamps

19-year follow up

High
0.02

Not statistically significant, p = 0.96

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Ever used Medicaid

19-year follow up

High
0.20

Not statistically significant, p = 0.44

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Effect rating key
Favorable finding / Statistically significant
Unfavorable finding / Statistically significant
Ambiguous finding / Statistically significant
No effect / Not statistically significant
Reductions in juvenile delinquency, family violence, and crime
Outcome measure Timing of follow-up Rating Direction of Effect Effect size (absolute value) Stastical significance Sample size Sample description

Arrested, lifetime

19-year follow-up

High
0.48

Statistically significant, p < 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Convicted, lifetime

19-year follow-up

High
0.64

Statistically significant, p < 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Arrested, past year

19-year follow-up

High
0.03

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Convicted, past year

19-year follow-up

High
0.34

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Felony assault

19-year follow-up

High
0.64

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Minor assault

19-year follow-up

High
0.10

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Minor theft

19-year follow-up

High
0.25

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Fraud

19-year follow-up

High
0.67

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Illegal services

19-year follow-up

High
0.34

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Vandalism

19-year follow-up

High
0.06

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Public disorder

19-year follow-up

High
0.18

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Number of arrests, lifetime

19-year follow-up

High

Statistically significant, p < 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Number of convictions, lifetime

19-year follow-up

High

Statistically significant, p < 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Number of arrests, past year

19-year follow-up

High

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Number of convictions, past year

19-year follow-up

High

Not statistically significant, p ≥ 0.05

231 children

Nurse visited during pregnancy and infancy and comparison (Elmira)

Arrested, lifetime

19-year follow-up

High
0.20

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Convicted, lifetime

19-year follow-up

High
0.16

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Arrested, past year

19-year follow-up

High
0.49

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Convicted, past year

19-year follow-up

High
0.56

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Felony assault

19-year follow-up

High
0.52

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Minor assault

19-year follow-up

High
0.03

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Minor theft

19-year follow-up

High
0.14

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Fraud

19-year follow-up

High
0.09

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Illegal services

19-year follow-up

High
0.07

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Vandalism

19-year follow-up

High
0.24

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Public disorder

19-year follow-up

High
0.13

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Number of arrests, lifetime

19-year follow-up

High

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Number of convictions, lifetime

19-year follow-up

High

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Number of arrests, past year

19-year follow-up

High

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Number of convictions, past year

19-year follow-up

High

Not statistically significant, p ≥ 0.05

219 children

Nurse visited during pregnancy and comparison (Elmira)

Subgroups
Outcome measure Timing of follow-up Rating Direction of Effect Effect size (absolute value) Stastical significance Sample size Sample description

Arrested, lifetime

19-year follow up

High
0.33

Statistically significant, p= <0.05

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Convicted, lifetime

19-year follow up

High
0.20

Statistically significant, p= <0.05

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Arrested, past year

19-year follow up

High
0.36

Not statistically significant, p = 0.61

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Convicted, past year

19-year follow up

High
0.10

Not statistically significant, p = 0.89

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Felony assault

19-year follow up

High
2.46

Not statistically significant, p = 0.40

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Minor assault

19-year follow up

High
0.19

Not statistically significant, p = 0.65

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Minor theft

19-year follow up

High
0.13

Not statistically significant, p = 0.81

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Fraud

19-year follow up

High
2.01

Not statistically significant, p = 0.49

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Illegal services

19-year follow up

High
0.36

Not statistically significant, p = 0.61

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Vandalism

19-year follow up

High
0.59

Not statistically significant, p = 0.30

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Public disorder

19-year follow up

High
0.23

Not statistically significant, p = 0.40

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Number of arrests, lifetime

19-year follow up

High
0.18

Statistically significant, p= <0.05

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Number of convictions, lifetime

19-year follow up

High
0.11

Statistically significant, p= <0.05

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Number of arrests, past year

19-year follow up

High
2.64

Statistically significant, p = 0.00

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Number of convictions, past year

19-year follow up

High
2.34

Statistically significant, p = 0.00

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (girls)

Arrested, lifetime - 15 year follow-up

15-year follow up

High
0.10

Not statistically significant, p = 0.88

117 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (boys)

Arrested, lifetime - 15 year follow-up

15-year follow up

High
1.30

Statistically significant, p = 0.00

124 children

Nurse visited during pregnancy + infancy and comparison (Elmira); Subgroup: Child gender (boys)

Effect rating key
Favorable finding / Statistically significant
Unfavorable finding / Statistically significant
Ambiguous finding / Statistically significant
No effect / Not statistically significant