Manuscript Details

Peer reviewed?
Yes

Goldfeld, S., Price, A., Smith, C., Bruce, T., Bryson, H., Mensah, F., Orsini, F., Gold, L., Hiscock, H., Bishop, L., Smith, A., Perlen, S., & Kemp, L. (2019). Nurse home visiting for families experiencing adversity: A randomized trial. Pediatrics, 143(1).

High rating
Study reviewed under: Handbook of Procedures and Standards, Version 2
Screening Conclusion

Eligible for review

Author Affiliation

The authors are affiliated with Murdoch Children’s Research Institute, The Royal Children’s Hospital, the University of Melbourne, the Australian Research Alliance for Children and Youth, Western Sydney University, and Deakin University in Australia. Dr. Kemp, a study author, is a developer of the MECSH home visiting program.

Funding Sources

This research was supported by the state governments of Victoria and Tasmania, the Ian Potter Foundation, Sabemo Trust, the Sidney Myer Fund, the Vincent Fairfax Family Foundation, and the National Health and Medical Research Council by Award Number 1079418.

Study Design
Design Attrition Baseline equivalence Confounding factors Valid, reliable measures?
Randomized controlled trial Low

Not assessed for randomized controlled trials with low attrition

No

Yes

Notes

Information to demonstrate equivalence of the intervention and comparison groups was based on correspondence with the author. Several findings received a low rating because the measures did not meet HomVEE’s reliability standards or reliability was not calculated. These included several subscales of the Home Observation for Measurement of the Environment (HOME) scale, measures of child’s mealtimes and food choices, bedtime routines, mother and child health, and language behaviors. In addition, several findings at 24 months old received an indeterminate rating—measures of mother’s planning future study, child stress, and sibling mental health—because the findings were high attrition and HomVEE could not assess whether the findings satisfied the baseline equivalence requirement based on the available information. Two outcomes were not eligible for review: Patient Satisfaction Index and Parent Enablement Index. These are measures of implementation of the home visiting evaluation, which are not eligible for review in one of HomVEE’s outcome domains.

Findings that rate moderate or high in this manuscript

Child Development and School Readiness
Outcome Measure Timing of Follow-Up Rating Direction of Effect Effect Size (Absolute Value) Stastical Significance Sample Size Sample Description
Child - Does things to get mother to laugh 24 months old High
0.63 Statistically significant, p= 0.01 586 children MECSH vs. comparison, Australia, 2013-2017, full sample
Child - Engages in pretend play 24 months old High
0.31 Not statistically significant, p= 0.05 589 children MECSH vs. comparison, Australia, 2013-2017, full sample
Child - Gets mother to notice things 24 months old High
0.46 Not statistically significant, p= 0.08 590 children MECSH vs. comparison, Australia, 2013-2017, full sample
Child - Nods to indicate yes 24 months old High
0.12 Not statistically significant, p= 0.25 581 children MECSH vs. comparison, Australia, 2013-2017, full sample
Child - Puts 2 words together 24 months old High
0.23 Not statistically significant, p= 0.14 587 children MECSH vs. comparison, Australia, 2013-2017, full sample
Child - Waves to greet people 24 months old High
0.08 Not statistically significant, p= 0.64 584 children MECSH vs. comparison, Australia, 2013-2017, full sample
Effect rating key
Favorable finding / Statistically significant
Unfavorable finding / Statistically significant
Ambiguous finding / Statistically significant
No effect / Not statistically significant
Child Health
Outcome Measure Timing of Follow-Up Rating Direction of Effect Effect Size (Absolute Value) Stastical Significance Sample Size Sample Description
Child - Ate breakfast today 24 months old High
0.50 Statistically significant, p= 0.01 589 children MECSH vs. comparison, Australia, 2013-2017, full sample
Child - Began solid foods at ages 4–6 months 24 months old High
0.15 Not statistically significant, p= 0.33 635 children MECSH vs. comparison, Australia, 2013-2017, full sample
Child - Only given water, milk, formula to drink 12 months old High
0.04 Not statistically significant, p= 0.93 633 children MECSH vs. comparison, Australia, 2013-2017, full sample
Mother - Breastfed until age 6 months 24 months old High
0.17 Not statistically significant, p= 0.16 566 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Mother - Ever breastfed 24 months old High
0.05 Not statistically significant, p= 0.64 668 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Effect rating key
Favorable finding / Statistically significant
Unfavorable finding / Statistically significant
Ambiguous finding / Statistically significant
No effect / Not statistically significant
Family Economic Self-Sufficiency
Outcome Measure Timing of Follow-Up Rating Direction of Effect Effect Size (Absolute Value) Stastical Significance Sample Size Sample Description
Mother - Currently studying 24 months old High
0.06 Not statistically significant, p= 0.65 582 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Mother - Employed 24 months old High
0.13 Not statistically significant, p= 0.13 581 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Effect rating key
Favorable finding / Statistically significant
Unfavorable finding / Statistically significant
Ambiguous finding / Statistically significant
No effect / Not statistically significant
Maternal Health
Outcome Measure Timing of Follow-Up Rating Direction of Effect Effect Size (Absolute Value) Stastical Significance Sample Size Sample Description
Assessment of Quality of Life (AQoL) 24 months old High
0.03 Not statistically significant, p= 0.78 571 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Depression, Anxiety, and Stress Scale‍ (DASS), Anxiety (reverse coded) 24 months old High
0.07 Not statistically significant, p= 0.34 574 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Depression, Anxiety, and Stress Scale‍ (DASS), Depression (reverse coded) 24 months old High
0.04 Not statistically significant, p= 0.55 573 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Depression, Anxiety, and Stress Scale‍ (DASS), Overall (reverse coded) 24 months old High
0.05 Not statistically significant, p= 0.52 571 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Depression, Anxiety, and Stress Scale‍ (DASS), Stress (reverse coded) 24 months old High
0.10 Not statistically significant, p= 0.26 573 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Maternal stress (hair cortisol, pg/mg; logtransformed) 24 months old High
0.08 Not statistically significant, p= 0.25 438 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Mother - Does not smoke 24 months old High
0.12 Not statistically significant, p= 0.14 587 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Mother - Does not smoke 12 months old High
0.02 Not statistically significant, p= 0.86 635 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Mother - High self-efficacy (item drawn from Longitudinal Study of Australian Children) 24 months old High
0.08 Not statistically significant, p= 0.25 568 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Personal Wellbeing Index (PWI) 24 months old High
0.04 Not statistically significant, p= 0.46 559 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Effect rating key
Favorable finding / Statistically significant
Unfavorable finding / Statistically significant
Ambiguous finding / Statistically significant
No effect / Not statistically significant
Positive Parenting Practices
Outcome Measure Timing of Follow-Up Rating Direction of Effect Effect Size (Absolute Value) Stastical Significance Sample Size Sample Description
Home Observation for Measurement of the Environment (HOME), Parental Responsivity 24 months old High
0.02 Not statistically significant, p= 0.74 546 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Hostile parenting (items drawn from Longitudinal Study of Australian Children; reverse coded) 24 months old High
0.24 Statistically significant, p= <.001 588 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Parenting Self-Efficacy Scale (items drawn from Longitudinal Study of Australian Children) 24 months old High
0.14 Statistically significant, p= 0.04 587 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Warm parenting (items drawn from Longitudinal Study of Australian Children) 24 months old High
0.20 Statistically significant, p= 0.01 582 mothers MECSH vs. comparison, Australia, 2013-2017, full sample
Effect rating key
Favorable finding / Statistically significant
Unfavorable finding / Statistically significant
Ambiguous finding / Statistically significant
No effect / Not statistically significant

This study included participants with the following characteristics at enrollment:

Race/Ethnicity

Data not available

Maternal Education

Less than a high school diploma
24%
High school diploma or GED
65%
Bachelor's degree or higher
11%

Other Characteristics

Data not available

This study included participants from the following locations:

  • State not reported or international
International Locations
Australia
Study Participants

Study participants were pregnant women recruited from prenatal clinics in public maternity hospitals across two states in Australia. To be eligible, women had to be at no more than 36 weeks of gestation, have sufficient knowledge of English to complete interviews, have two or more risk factors identified at screening from a list of 10 for poor child outcomes, and their home addresses had to be within travel boundaries of the participating areas. A total of 722 pregnant women were randomly assigned to either the home visiting intervention (363 women) or the comparison condition (359 women). Outcomes were measured when children were 12 and 24 months. Up to 668 women were included in the analyses at 24 months (339 in the intervention group and 329 in the comparison group). In the study, 24 percent of mothers did not complete high school, 65 percent completed high school or vocational training, and 11 percent had a university degree.

Setting

The study took place in Victoria and Tasmania in Australia.

Comparison Conditions

Mothers in the comparison group received six to nine consultations with a nurse until the child reached 24 months. The first consultation occurred in families’ homes and other occurred at local centers. The consultations focused on broad-ranging supports for child health and development as well as parental well-being.

Were any subgroups examined?
No
Subgroups examined

• Parity (primiparous or multiparous) • Antenatal risk factors (2 or fewer risk factors or 3 or more risk factors) • Overall mental health (higher than the 85th percentile for mental health or less than the 85th percentile) • Maternal self-efficacy (high or low)