Smith, J. D., Wakschlag, L., Krogh-Jespersen, S., Walkup, J. T., Wilson, M. N., Dishion, T. J., & Shaw, D. S. (2019). Dysregulated irritability as a window on young children's psychiatric risk: Transdiagnostic effects via the Family Check-Up. Development and Psychopathology, 31(5), 1887–1899.
| Screening decision | Screening conclusion | HomVEE procedures and standards version |
|---|---|---|
| Passes screens | Eligible for review | Version 2 |
| Rating | Design | Attrition | Baseline equivalence | Compromised randomization | Confounding factors | Valid, reliable measure(s) |
|---|---|---|---|---|---|---|
| Low | Randomized controlled trial | Not applicable | Not applicable |
No | No |
No |
This manuscript presents a path model. In the path model, the direct effect on irritability at age 4 was eligible for HomVEE review. This finding received a low evidence rating because HomVEE could not confirm the reliability of the outcome measure. In this same model, the indirect effects on oppositional and defiant behavior, and depression and anxiety symptoms, were ineligible for review because HomVEE does not review indirect effects in path models. The effects on irritability at ages 3 and 4, as examined through another path model (the unconditional model), were ineligible for review because HomVEE was unable to obtain a path diagram for this model.
Clinicaltrials.gov Identifier: NCT01098695. SocialScienceRegistry.org Identifier: None found. Registry of Efficacy and Effectiveness Studies Identifier: None found. Study registration was assessed by HomVEE for Clinicaltrials.gov beginning with the 2014 review, and for other registries beginning with the 2021 review.