Black or African American
22%
Source
Klinnert, M. D., Liu, A. H., Pearson, M. R., Ellison, M. C., Budhiraja, N., & Robinson, J. L. (2005). Short-term impact of a randomized multifaceted intervention for wheezing infants in low-income families. Archives of Pediatrics & Adolescent Medicine, 159(1), 75-82.
Model(s) Reviewed
Funding Sources
National Institute of Allergy and Infectious Diseases; National Institute of Health/National Center for Research Resources.
Study Design
| Design | Attrition | Baseline equivalence | Confounding factors | Valid, reliable measures? |
|---|---|---|---|---|
| Randomized controlled trial | Low | Not applicable | None |
Notes
High rating applies to most outcomes. Medical record outcomes receive a low rating because of high attrition and failure to demonstrate baseline equivalence.
Study Participants
Participants (infants and their families) were recruited from local hospitals and clinics in the Denver, Colorado, area and assigned randomly to either the intervention or the comparison group. Initially 181 infants were randomly assigned, 90 to the treatment group and 91 to the comparison group. At baseline, the study groups were split among European Americans (22 percent treatment, 21 percent control), African American (23 percent treatment, 22 percent control), U.S.-born Hispanic (33 percent treatment, 31 percent control) and foreign-born Hispanic (22 percent treatment, 20 percent control). Approximately half of each group had incomes less than $12,000 per year. Participants were followed for one year after baseline data were collected.
Setting
The study was conducted in Denver, Colorado.
Home Visiting Services
The intervention included home visits conducted by specially trained nurses. The intervention began when infants were from 9 to 24 months old and continued for 12 months. Participants received approximately 15 visits (or telephone calls) by a public health nurse. Each visit lasted an average of 53 minutes.
Comparison Conditions
Comparison group members received an educational video at the baseline interview that described risk factors for developing asthma and actions that caregivers can take to mediate the risks.
Study Participants
Participants (infants and their families) were recruited from local hospitals and clinics in the Denver, Colorado, area and assigned randomly to either the intervention or the comparison group. Initially 181 infants were randomly assigned, 90 to the treatment group and 91 to the comparison group. At baseline, the study groups were split among European Americans (22 percent treatment, 21 percent control), African American (23 percent treatment, 22 percent control), U.S.-born Hispanic (33 percent treatment, 31 percent control) and foreign-born Hispanic (22 percent treatment, 20 percent control). Approximately half of each group had incomes less than $12,000 per year. Participants were followed for one year after baseline data were collected.
Setting
The study was conducted in Denver, Colorado.
Home Visiting Services
The intervention included home visits conducted by specially trained nurses. The intervention began when infants were from 9 to 24 months old and continued for 12 months. Participants received approximately 15 visits (or telephone calls) by a public health nurse. Each visit lasted an average of 53 minutes.
Comparison Conditions
Comparison group members received an educational video at the baseline interview that described risk factors for developing asthma and actions that caregivers can take to mediate the risks.
Findings that rate moderate or high in this manuscript
| Outcome measure | Timing of follow-up | Rating | Direction of Effect | Effect size (absolute value) | Stastical significance | Sample size | Sample description | |
|---|---|---|---|---|---|---|---|---|
| Cotinine level | 12 months | High | 0.25 | Not statistically significant, p = 0.28 | 130 children | Denver, Colorado sample | ||
| Functional Severity Score | 12 months | High | Not Statistically significant, p = 0.60 | 150 children | Denver, Colorado sample |
| Outcome measure | Timing of follow-up | Rating | Direction of Effect | Effect size (absolute value) | Stastical significance | Sample size | Sample description | |
|---|---|---|---|---|---|---|---|---|
| Asthma knowledge score | 12 months | High | Statistically significant, p = 0.04 | 150 parents | Denver, Colorado sample | |||
| Collaborative relationship score | 12 months | High | Statistically significant, p = 0.04 | 146 parents | Denver, Colorado sample | |||
| HOME score | 12 months | High | Not statistically significant, p = 0.94 | 137 parents | Denver, Colorado sample | |||
| Cockroach allergen | 12 months | High | 1.62 | Statistically significant, p = 0.03 | 140 parents | Denver, Colorado sample | ||
| Cat dander | 12 months | High | 0.20 | Not statistically significant, p = 0.25 | 140 parents | Denver, Colorado sample | ||
| Dog dander | 12 months | High | 0.45 | Not statistically significant, p = -.07 | 141 parents | Denver, Colorado sample |
| Outcome measure | Timing of follow-up | Rating | Direction of Effect | Effect size (absolute value) | Stastical significance | Sample size | Sample description | |
|---|---|---|---|---|---|---|---|---|
| Caregiver quality of life score | 12 months | High | Not statistically significant, p = 0.72 | 143 parents | Denver, Colorado sample |
This study included participants with the following characteristics at enrollment:
Race/Ethnicity
Maternal Education
Other Characteristics
This study included participants from the following locations:
- Colorado