Black or African American
22%
Klinnert, M. D., Liu, A. H., Pearson, M. R., Ellison, M. C., Budhiraja, N., & Robinson, J. L. (2005). Short-term impact of a randomized multifaceted intervention for wheezing infants in low-income families. Archives of Pediatrics & Adolescent Medicine, 159(1), 75-82.
Model(s): Childhood Asthma Prevention Study (CAPS)
Study design characteristics contributing to rating
| Design | Attrition | Baseline equivalence | Confounding factors? | Valid, reliable measures? |
|---|---|---|---|---|
| Randomized controlled trial | Low |
Not applicable |
None |
Not assessed in manuscripts reviewed under Handbook of Procedures and Standards, Version 1 |
Notes from the review of this manuscript
High rating applies to most outcomes. Medical record outcomes receive a low rating because of high attrition and failure to demonstrate baseline equivalence.
Child Health
| Outcome Measure | Timing of Follow-Up | Rating | Direction of Effect | Effect Size (Absolute Value) | Stastical Significance | Sample Size | Sample Description |
|---|---|---|---|---|---|---|---|
| Cotinine level | 12 months | High | 0.25 | Not statistically significant, p = 0.28 | 130 children | Denver, Colorado sample | |
| Functional Severity Score | 12 months | High | Not Statistically significant, p = 0.60 | 150 children | Denver, Colorado sample |
Maternal Health
| Outcome Measure | Timing of Follow-Up | Rating | Direction of Effect | Effect Size (Absolute Value) | Stastical Significance | Sample Size | Sample Description |
|---|---|---|---|---|---|---|---|
| Caregiver quality of life score | 12 months | High | Not statistically significant, p = 0.72 | 143 parents | Denver, Colorado sample |
Positive Parenting Practices
| Outcome Measure | Timing of Follow-Up | Rating | Direction of Effect | Effect Size (Absolute Value) | Stastical Significance | Sample Size | Sample Description |
|---|---|---|---|---|---|---|---|
| HOME score | 12 months | High | Not statistically significant, p = 0.94 | 137 parents | Denver, Colorado sample | ||
| Asthma knowledge score | 12 months | High | Statistically significant, p = 0.04 | 150 parents | Denver, Colorado sample | ||
| Cat dander | 12 months | High | 0.20 | Not statistically significant, p = 0.25 | 140 parents | Denver, Colorado sample | |
| Cockroach allergen | 12 months | High | 1.62 | Statistically significant, p = 0.03 | 140 parents | Denver, Colorado sample | |
| Collaborative relationship score | 12 months | High | Statistically significant, p = 0.04 | 146 parents | Denver, Colorado sample | ||
| Dog dander | 12 months | High | 0.45 | Not statistically significant, p = -.07 | 141 parents | Denver, Colorado sample |
This study included participants from the following locations:
- Colorado
Study Participants
Participants (infants and their families) were recruited from local hospitals and clinics in the Denver, Colorado, area and assigned randomly to either the intervention or the comparison group. Initially 181 infants were randomly assigned, 90 to the treatment group and 91 to the comparison group. At baseline, the study groups were split among European Americans (22 percent treatment, 21 percent control), African American (23 percent treatment, 22 percent control), U.S.-born Hispanic (33 percent treatment, 31 percent control) and foreign-born Hispanic (22 percent treatment, 20 percent control). Approximately half of each group had incomes less than $12,000 per year. Participants were followed for one year after baseline data were collected.
Setting
The study was conducted in Denver, Colorado.
Intervention condition
Note: Navigate to the model page for more information about the home visiting model. See the source manuscript for more information about how the model was implemented in this study.
Comparison Conditions
Comparison group members received an educational video at the baseline interview that described risk factors for developing asthma and actions that caregivers can take to mediate the risks.
Funding Sources
National Institute of Allergy and Infectious Diseases; National Institute of Health/National Center for Research Resources.