Olds, D. L., Kitzman, H. J., Cole, R. E., Hanks, C. A., Arcoleo, K. J., Anson, E. A., Luckey, D. W., Knudtson, M. D., Henderson, C. R., Bondy, J., & Stevenson, A. J. (2010). Enduring effects of prenatal and infancy home visiting by nurses on maternal life course and government spending: Follow-up of a randomized trial among children at age 12 years. Archives of Pediatrics & Adolescent Medicine, 164(5), 419-424
Model(s) Reviewed:
Nurse-Family Partnership (NFP)®
| Screening decision | Screening conclusion | HomVEE procedures and standards version |
|---|---|---|
| Passes screens | Eligible for review | Version 1 |
| Rating | Design | Attrition | Baseline equivalence | Compromised randomization | Confounding factors | Valid, reliable measure(s) |
|---|---|---|---|---|---|---|
| High | Randomized controlled trial | Low | Established for race/ethnicity. Significant differences in SES, but controlled in analyses. | None | None | Not assessed in manuscripts reviewed before 2021 |
Notes:
In 2020, HomVEE updated this review to remove three mother's partnership status/family structure findings from the Family Economic Self-Sufficiency domain because ACF determined that mother's partnership status is ineligible for review by HomVEE.
| Study participants | The authors recruited women from the obstetric and pediatric care public system. A total of 743 pregnant women were enrolled and randomly assigned to treatment (228 women) or comparison (515 women). At the study’s onset, 92 percent of women in the sample were African American, 98.1 percent were unmarried, 64.1 percent were younger than 19 years, and 85 percent were living in households with incomes below the federal poverty threshold. For the 12-year follow-up, 594 women were interviewed. This sample is the same as that described in Kitzman et al. (2010) and reports on different outcomes from those described in that study. |
|---|---|
| Setting | Memphis, TN |
| Intervention services | Mothers in the nurse-visited condition were provided home visiting from pregnancy through their child’s second birthday, and the same assessment and referrals and transportation services provided to those in the comparison group. |
| Comparison conditions | Mothers in the comparison group were provided developmental screening and referral services for their child at age 6, 12, and 24 months, and free transportation for scheduled prenatal care. |
| Subgroups examined |
This field lists subgroups examined in the manuscript (even if they were not replicated in other samples and not reported on the summary page for this model’s report). Subgroups are not listed for manuscripts reviewed before 2021. |
| Funding sources | This project was supported by grant 1R01MH68790-01 from the National Institute of Mental Health, National Institutes of Health, and by grant 2004-52854-CO-JS0 from the Office of Juvenile Justice and Delinquency Prevention. |
| Author affiliation | David L. Olds, a study author, is a developer of this model. |
| Peer reviewed | Peer reviewed status is not listed for manuscripts reviewed before 2021. |
Findings that rate moderate or high
| Rating | Outcome measure | Effect | Sample | Timing of follow-up | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| High | Use of AFDC-TANF | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis | 0 to 12 years | 594 mothers | Adjusted mean = 4.97 | Adjusted mean = 5.47 | Mean difference = -0.50 | HomVEE calculated = -3.03 | Statistically significant, p < .05 | |
| High | Time employed, in months | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 2 to 12 years | 594 mothers | Adjusted mean = 4.50 | Adjusted mean = 4.64 | Mean difference = -0.14 | HomVEE calculated = -0.99 | Not statistically significant, p ≥ 0.05 | |
| High | Time employed, in months | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 10 to 12 years | 594 mothers | Adjusted mean = 7.10 | Adjusted mean = 7.77 | Mean difference = -0.67 | HomVEE calculated = -2.62 | Not statistically significant, p ≥ 0.05 | |
| High | Use of AFDC-TANF | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 10 to 12 years | 594 mothers | Adjusted mean = 3.75 | Adjusted mean = 3.97 | Mean difference = -0.22 | HomVEE calculated = -13.10 | Not statistically significant, p ≥ 0.05 | |
| High | Use of food stamps | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 0 to 12 years | 594 mothers | Adjusted mean = 6.27 | Adjusted mean = 6.86 | Mean difference = -0.59 | HomVEE calculated = -3.90 | Statistically significant, p < .05 | |
| High | Use of food stamps | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 10 to 12 years | 594 mothers | Adjusted mean = 4.46 | Adjusted mean = 5.06 | Mean difference = -0.60 | HomVEE calculated = -2.65 | Not statistically significant, p ≥ 0.05 | |
| High | Use of Medicaid | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 0 to 12 years | 594 mothers | Adjusted mean = 8.08 | Adjusted mean = 8.39 | Mean difference = -0.31 | HomVEE calculated = -1.88 | Not statistically significant, p ≥ 0.05 | |
| High | Use of Medicaid | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 10 to 12 years | 594 mothers | Adjusted mean = 6.02 | Adjusted mean = 6.23 | Mean difference = -0.21 | HomVEE calculated = -0.81 | Not statistically significant, p ≥ 0.05 |
| Rating | Outcome measure | Effect | Sample | Timing of follow-up | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| High | Pearlin Mastery Scale | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy + infancy and development screening comparison (Memphis) | 6 months to 12 years | 594 mothers | Adjusted mean = 101.04 | Adjusted mean = 99.60 | Mean difference = 1.44 | HomVEE calculated = 4.30 | Statistically significant, p < .05 | |
| High | Pearlin Mastery Scale | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy + infancy and development screening comparison (Memphis) | 12-year follow-up | 594 mothers | Adjusted mean = 101.07 | Adjusted mean = 99.56 | Mean difference = 1.51 | HomVEE calculated = 2.80 | Not statistically significant, p ≥ 0.05 | |
| High | Alcohol or other drug use | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 12-year follow-up | 594 mothers | %(adjusted) = 10.00 | Adjusted mean % = 10.00 | OR = 0.91 | HomVEE calculated = -0.05 | Not statistically significant, p ≥ 0.05 | |
| High | Cumulative subsequent births | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 0 to 12 years | 594 mothers | Adjusted mean = 1.07 | Adjusted mean = 1.15 | Mean difference = -0.08 | HomVEE calculated = -1.69 | Not statistically significant, p ≥ 0.05 | |
| High | Cumulative subsequent births | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 10 to 12 years | 594 mothers | Adjusted mean = 1.80 | Adjusted mean = 1.83 | Mean difference = -0.03 | HomVEE calculated = -0.42 | Not statistically significant, p ≥ 0.05 | |
| High | Role impairment due to alcohol or drug use | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 12-year follow-up | 594 mothers | %(adjusted) = 0.00 | Adjusted mean % = 3.00 | Difference = -0.03 | Not available | Statistically significant, p < .05 | |
| High | Symptoms of psychological distress (borderline/clinical vs. normal) | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 12-year follow-up | 594 mothers | %(adjusted) = 18.00 | Adjusted mean % = 17.00 | OR = 1.09 | HomVEE calculated = 0.05 | Not statistically significant, p ≥ 0.05 |
| Rating | Outcome measure | Effect | Sample | Timing of follow-up | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| High | Child foster care placements | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 0 to 12 years | 594 mothers | %(adjusted) = 12.00 | Adjusted mean % = 4.00 | OR = 3.33 | HomVEE calculated = 0.72 | Not statistically significant, p ≥ 0.05 |
| Rating | Outcome measure | Effect | Sample | Timing of follow-up | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| High | Intimate partner violence | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 12-year follow-up | 594 mothers | %(adjusted) = 22.00 | Adjusted mean % = 21.00 | OR = 1.06 | HomVEE calculated = 0.03 | Not statistically significant, p ≥ 0.05 | |
| High | Maternal arrests | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 0 to 12 years | 594 mothers | %(adjusted) = 49.00 | Adjusted mean % = 36.00 | OR = 1.36 | HomVEE calculated = 0.32 | Not statistically significant, p ≥ 0.05 | |
| High | Mother jailed | FavorableUnfavorable or ambiguousNo Effect |
Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 12-year follow-up | 594 mothers | % (adjusted) = 13.00 | Adjusted mean % = 13.00 | OR = 0.97 | HomVEE calculated = -0.02 | Not statistically significant, p ≥ 0.05 |