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Whitehouse, A. J., Varcin, K. J., Alvares, G. A., Barbaro, J., Bent, C., Boutrus, M., ... & Hudry, K. (2019). Pre-emptive intervention versus treatment as usual for infants showing early behavioural risk signs of autism spectrum disorder: a single-blind, randomised controlled trial. The Lancet Child & Adolescent Health, 3(9), 605-615.

Manuscript screening details
Screening decision Screening conclusion HomVEE procedures and standards version
Passes screens Eligible for review Version 2
Study design details
Rating Design Attrition Baseline equivalence Compromised randomization Confounding factors Valid, reliable measure(s)
Low Randomized controlled trial High

Not established on race/ethnicity, SES, or baseline measures of the outcome(s) in the analyzed sample

No

No

Measure validity and reliability is not assessed for findings that receive a low evidence rating; all findings in this manuscript rate low

Study Registration:

Clinicaltrials.gov Identifier: None found. SocialScienceRegistry.org Identifier: None found. Registry of Efficacy and Effectiveness Studies Identifier: None found. Study registration was assessed by HomVEE for Clinicaltrials.gov beginning with the 2014 review, and for other registries beginning with the 2021 review.