Statistical significance is based on HomVEE calculations.
Nurse-Family Partnership (NFP)®
Model effectiveness research report last updated: 2024
Effects shown in research
Maternal health
Findings rated high
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
Mental health - Anxiety: Mental Health Inventory (MHI) |
FavorableUnfavorable or ambiguousNo Effect |
15 years |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
300 mothers | Unadjusted mean = 2.56 | Unadjusted mean = 2.56 | MD = 0.00 | HomVEE calculated = 0.00 | Not statistically significant, p = 1.00 |
|
Mental health - Depression: Mental Health Inventory (MHI) |
FavorableUnfavorable or ambiguousNo Effect |
15 years |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
300 mothers | Unadjusted mean = 2.01 | Unadjusted mean = 2.02 | MD = -0.01 | HomVEE calculated = -0.01 | Not statistically significant, p = 0.95 |
Statistical significance is based on HomVEE calculations. |
Mental health - Emotional stability: Mental Health Inventory (MHI) |
FavorableUnfavorable or ambiguousNo Effect |
15 years |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
300 mothers | Unadjusted mean = 3.75 | Unadjusted mean = 3.74 | MD = 0.01 | HomVEE calculated = 0.02 | Not statistically significant, p = 0.90 |
Statistical significance is based on HomVEE calculations. |
Mental health - Positive well-being: Mental Health Inventory (MHI) |
FavorableUnfavorable or ambiguousNo Effect |
15 years |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
300 mothers | Unadjusted mean = 3.78 | Unadjusted mean = 3.79 | MD = -0.01 | HomVEE calculated = -0.02 | Not statistically significant, p = 0.90 |
Statistical significance is based on HomVEE calculations. |
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| Anxiety (MHI), 24 months postpartum, standardized | FavorableUnfavorable or ambiguousNo Effect |
2 years postpartum | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 mothers | Adjusted mean = 99.10 | Adjusted mean = 100.30 | Mean difference = -1.20 | Not available | Not statistically significant, p ≥ 0.05 | |
| Depression (MHI), 24 months postpartum, standardized | FavorableUnfavorable or ambiguousNo Effect |
2 years postpartum | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 mothers | Adjusted mean = 99.50 | Adjusted mean = 100.10 | Mean difference = -0.06 | Not available | Not statistically significant, p ≥ 0.05 | |
| Diastolic blood pressure | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | Adjusted mean = 66.80 | Adjusted mean = 67.50 | Mean difference = -0.70 | Not available | Not statistically significant, p ≥ 0.05 | This mean difference, calculated by HomVEE, is within |0.01| of the difference reported by the authors, with the discrepancy likely due to rounding error.
|
| Gestational weight gain | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | Adjusted mean = 14.60 | Adjusted mean = 14.90 | Mean difference = -0.30 | Not available | Not statistically significant, p ≥ 0.05 | |
| Number of Gardnerella infections | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | Adjusted mean = 0.06 | Adjusted mean = 0.07 | Mean difference = -0.01 | Not available | Not statistically significant, p ≥ 0.05 | Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of hospitalizations during pregnancy | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | Adjusted mean = 0.15 | Adjusted mean = 0.13 | Mean difference = 0.02 | Not available | Not statistically significant, p ≥ 0.05 | Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of sexually transmitted diseases | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | Adjusted mean = 0.22 | Adjusted mean = 0.21 | Mean difference = 0.01 | Not available | Not statistically significant, p ≥ 0.05 | Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of yeast infections | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | Adjusted mean = 0.14 | Adjusted mean = 0.19 | Mean difference = -0.05 | Not available | Statistically significant, p ≤ 0.05 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Obstetrical evaluation visits (total) | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | Adjusted mean = 2.80 | Adjusted mean = 2.80 | Mean difference = 0.00 | Not available | Not statistically significant, p ≥ 0.05 | This mean difference, calculated by HomVEE, is within |0.01| of the difference reported by the authors, with the discrepancy likely due to rounding error.
|
| Pearlin Mastery, 24 months postpartum, standardized | FavorableUnfavorable or ambiguousNo Effect |
2 years postpartum | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 mothers | Adjusted mean = 101.60 | Adjusted mean = 99.40 | Mean difference = 2.20 | Not available | Statistically significant, p < 0.01 |
|
| Pregnancy-induced hypertension (percentage) | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | % (adjusted) = 13.00 | Adjusted mean % = 20.00 | OR = 0.60 | HomVEE calculated = -0.31 | Statistically significant, p ≤ 0.01 |
Statistical significance reported on authors’ calculations of the odds ratio.
The odds ratio compares the nurse-visited group to the comparison.
|
| Spontaneous abortion, 0–24 months postpartum (percentage) | FavorableUnfavorable or ambiguousNo Effect |
2 years postpartum | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 mothers | % (adjusted) = 5.00 | Adjusted mean % = 3.00 | OR = 1.50 | HomVEE calculated = 0.32 | Not statistically significant, p ≥ 0.05 | The odds ratio compares the nurse-visited group to the comparison.
|
| Standard prenatal care visits (total) | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | Adjusted mean = 6.20 | Adjusted mean = 6.50 | Mean difference = -0.30 | Not available | Not statistically significant, p ≥ 0.05 | |
| Subsequent live birth, 0–24 months postpartum (percentage) | FavorableUnfavorable or ambiguousNo Effect |
2 years postpartum | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 mothers | % (adjusted) = 22.00 | Adjusted mean % = 31.00 | OR = 0.60 | HomVEE calculated = -0.28 | Statistically significant, p < 0.01 |
Statistical significance reported on authors’ calculations of the odds ratio.
The odds ratio compares the nurse-visited group to the comparison.
|
| Subsequent pregnancy, 0-24 months postpartum (percentage) | FavorableUnfavorable or ambiguousNo Effect |
2 years postpartum | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 mothers | % (adjusted) = 36.00 | Adjusted mean % = 47.00 | OR = 0.60 | HomVEE calculated = -0.28 | Statistically significant, p < 0.01 |
Statistical significance reported on authors’ calculations of the odds ratio.
The odds ratio compares the nurse-visited group to the comparison.
|
| Systolic blood pressure | FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy | Full (Memphis) | 916 mothers | Adjusted mean = 111.70 | Adjusted mean = 112.60 | Mean difference = -0.90 | Not available | Not statistically significant, p ≥ 0.05 | |
| Therapeutic abortion, 0–24 months postpartum (percentage) | FavorableUnfavorable or ambiguousNo Effect |
2 years postpartum | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 mothers | % (adjusted) = 2.00 | Adjusted mean % = 4.00 | OR = 0.50 | HomVEE calculated = -0.43 | Not statistically significant, p ≥ 0.05 | The odds ratio compares the nurse-visited group to the comparison.
|
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| Number of months between birth or first and second child | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Adjusted mean = 30.25 | Adjusted mean = 26.60 | Mean difference = 3.65 | Not available | Statistically significant, p ≤ 0.01 |
|
| Number of subsequent live births | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Adjusted mean = 0.85 | Adjusted mean = 0.96 | Mean difference = -0.11 | Not available | Not statistically significant, p ≥ 0.05 |
|
| Number of subsequent pregnancies | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Adjusted mean = 1.15 | Adjusted mean = 1.34 | Mean difference = -0.19 | Not available | Statistically significant, p < 0.05 |
|
| Number of subsequent pregnancies with short intervals (< 6 months from previous delivery or termination) | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Adjusted mean = 0.22 | Adjusted mean = 0.32 | Mean difference = -0.10 | Not available | Statistically significant, p < 0.05 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of subsequent spontaneous abortions | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Adjusted mean = 0.10 | Adjusted mean = 0.12 | Mean difference = -0.12 | Not available | Not statistically significant, p ≥ 0.05 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of subsequent still births | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Adjusted mean = 0.01 | Adjusted mean = 0.02 | Mean difference = -0.01 | Not available | Not statistically significant p ≥ 0.05 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of subsequent therapeutic abortions | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Adjusted mean = 0.05 | Adjusted mean = 0.10 | Mean difference = -0.05 | Not available | Not statistically significant, p ≥ 0.05 |
Authors report the difference in this outcome to be statistically significant, p < 0.10, which is greater than the acceptable alpha for this review (α = 0.05).
|
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
Current smoker |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
907 mothers | Adjusted proportion = 0.13 | Adjusted proportion = 0.12 | Difference = 0.00 | Study reported = 0.02 | Not statistically significant, p ≥ 0.05 |
Negative effect is favorable to the intervention. The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. |
Parenting Stress Index - Short Form (PSI-SF), parent-child dysfunctional interaction |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
914 mothers | Adjusted mean = 10.30 | Adjusted mean = 11.10 | Difference = -0.80 | Not available | Statistically significant, p < 0.05 |
Negative effect is favorable to the intervention. The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. The study reported this finding was statistically significant (p = 0.001) prior to a multiple comparisons adjustment, and remained significant after the adjustment. |
Parenting Stress Index - Short Form (PSI-SF), parental distress |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
917 mothers | Adjusted mean = 11.10 | Adjusted mean = 11.40 | Difference = -0.30 | Not available | Not statistically significant, p ≥ 0.05 |
Negative effect is favorable to the intervention. HomVEE calculated the adjusted intervention group mean by adding the reported adjusted comparison group mean to the reported estimated effect. The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. |
Received any behavioral health services |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
906 mothers | Adjusted proportion = 0.05 | Adjusted proportion = 0.04 | Difference = 0.00 | Study reported = 0.06 | Not statistically significant, p ≥ 0.05 |
The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. |
Substance use during the past three months |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
908 mothers | Adjusted proportion = 0.17 | Adjusted proportion = 0.12 | Difference = 0.05 | Study reported = 0.27 | Not statistically significant, p ≥ 0.05 |
Negative effect is favorable to the intervention. The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. The study reported this finding was statistically significant (p = 0.02) prior to a multiple comparisons adjustment. |
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
Any smoking during third trimester (%) |
FavorableUnfavorable or ambiguousNo Effect |
Birth |
NFP vs. Resource referral RCT (MIHOPE-Strong Start), 2012-2015, United States, full sample |
1404 mothers | Not reported | Not reported | Difference = 0.01 | Not available | Not statistically significant, p= 0.23 |
Negative effect is favorable to the intervention. |
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
Cesarean delivery |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
4932 mothers | Adjusted proportion = 0.31 Cases | Adjusted proportion = 0.33 Cases | Mean difference = -0.02 | Study reported = -0.06 | Not statistically significant, p= ≥0.05 |
Negative effect is favorable to the intervention. |
Severe maternal morbidity |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
5158 mothers | Adjusted proportion = 0.02 Cases | Adjusted proportion = 0.01 Cases | Mean difference = 0.00 | Study reported = 0.13 | Not statistically significant, p= ≥0.05 |
Negative effect is favorable to the intervention. |
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
|---|---|---|---|---|---|---|---|---|---|
New pregnancy after study entry, % (fixed effect random slope analysis) |
FavorableUnfavorable or ambiguousNo Effect |
15 months old |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States, full sample |
903 mothers | Not reported | Not reported | Difference = 0.00 | Not available | Not statistically significant, p= 0.97 |
New pregnancy after study entry, % (restricted maximum likelihood analysis) |
FavorableUnfavorable or ambiguousNo Effect |
15 months old |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States, full sample |
903 mothers | Not reported | Not reported | Difference = 0.00 | Not available | Not statistically significant, p= 0.98 |
New pregnancy after study entry, % (split-sample analysis) |
FavorableUnfavorable or ambiguousNo Effect |
15 months old |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States, full sample |
903 mothers | Not reported | Not reported | Difference = 0.02 | HomVEE calculated = 0.09 | Not statistically significant, p= 0.40 |
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| Incidence of substance use impairments | FavorableUnfavorable or ambiguousNo Effect |
15-year follow-up | Nurse visited during pregnancy + infancy and comparison (Elmira) | 245 mothers | Adjusted mean = 0.34 | Adjusted mean = 0.43 | Mean difference = -0.09 | Not available | Not statistically significant, p ≥ 0.05 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Months between birth of first and second child | FavorableUnfavorable or ambiguousNo Effect |
15-year follow-up | Nurse visited during pregnancy + infancy and comparison (Elmira) | 245 mothers | Adjusted mean = 41.70 | Adjusted mean = 37.30 | Mean difference = 4.40 | Not available | Not statistically significant, p ≥ 0.05 |
|
| Months between birth of first and second child | FavorableUnfavorable or ambiguousNo Effect |
15-year follow-up | Nurse visited during pregnancy and comparison (Elmira) | 227 mothers | Adjusted mean = 39.80 | Adjusted mean = 37.30 | Mean difference = 2.50 | Not available | Statistical significance not reported | |
| Subsequent births | FavorableUnfavorable or ambiguousNo Effect |
15-year follow-up | Nurse visited during pregnancy and comparison (Elmira) | 227 mothers | Adjusted mean = 1.40 | Adjusted mean = 1.60 | Mean difference = -0.20 | Not available | Statistical significance not reported | |
| Subsequent births | FavorableUnfavorable or ambiguousNo Effect |
15-year follow-up | Nurse visited during pregnancy + infancy and comparison (Elmira) | 245 mothers | Adjusted mean = 1.30 | Adjusted mean = 1.60 | Mean difference = -0.30 | Not available | Not statistically significant, p ≥ 0.05 |
|
| Subsequent pregnancies | FavorableUnfavorable or ambiguousNo Effect |
15-year follow-up | Nurse visited during pregnancy and comparison (Elmira) | 227 mothers | Adjusted mean = 1.90 | Adjusted mean = 2.10 | Mean difference = -0.20 | Not available | Statistical significance not reported | |
| Subsequent pregnancies | FavorableUnfavorable or ambiguousNo Effect |
15-year follow-up | Nurse visited during pregnancy + infancy and comparison (Elmira) | 245 mothers | Adjusted mean = 1.70 | Adjusted mean = 2.10 | Mean difference = -0.40 | Not available | Not statistically significant, p ≥ 0.05 |
|
| Substance use impairments since birth of first child | FavorableUnfavorable or ambiguousNo Effect |
15-year follow-up | Nurse visited during pregnancy and comparison (Elmira) | 227 mothers | Adjusted mean = 0.45 | Adjusted mean = 0.43 | Mean difference = 0.02 | Not available | Statistical significance not reported |
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| Number of births including first born (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy + infancy and comparison (Elmira) | 216 mothers | Adjusted mean = 1.65 | Adjusted mean = 1.85 | Mean difference = -0.20 | Not available | Not statistically significant, p ≥ 0.05 | Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of births including first born (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy and comparison (Elmira) | 203 mothers | Adjusted mean = 1.77 | Adjusted mean = 1.85 | Mean difference = -0.08 | Not available | Statistical significance not reported | |
| Number of months between first and second child (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy + infancy and comparison (Elmira) | 216 mothers | Adjusted mean = 40.76 | Adjusted mean = 37.11 | Mean difference = 3.65 | Not available | Not statistically significant, p ≥ 0.05 | Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of months between first and second child (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy and comparison (Elmira) | 203 mothers | Adjusted mean = 41.58 | Adjusted mean = 37.11 | Mean difference = 4.47 | Not available | Statistical significance not reported | |
| Number of pregnancies (0–22 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
22 months postpartum | Nurse visited during pregnancy and comparison (Elmira) | 188 mothers | Adjusted mean = 0.31 | Adjusted mean = 0.44 | Mean difference = -0.13 | Not available | Statistical significance not reported | |
| Number of pregnancies (0–22 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
22 months, postpartum | Nurse visited during pregnancy + infancy and comparison (Elmira) | 196 mothers | Adjusted mean = 0.38 | Adjusted mean = 0.44 | Mean difference = -0.06 | Not available | Not statistically significant, p ≥ 0.05 | Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of pregnancies (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy + infancy and comparison (Elmira) | 205 mothers | Adjusted mean = 0.82 | Adjusted mean = 1.06 | Mean difference = -0.24 | Not available | Not statistically significant, p ≥ 0.05 | Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of pregnancies (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy and comparison (Elmira) | 194 mothers | Adjusted mean = 0.90 | Adjusted mean = 1.06 | Mean difference = -0.16 | Not available | Statistical significance not reported | |
| Number of spontaneous abortions (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy + infancy and comparison (Elmira) | 205 mothers | Adjusted mean = 0.10 | Adjusted mean = 0.13 | Mean difference = -0.03 | Not available | Not statistically significant, p ≥ 0.05 | Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of spontaneous abortions (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy and comparison (Elmira) | 194 mothers | Adjusted mean = 0.12 | Adjusted mean = 0.13 | Mean difference = -0.01 | Not available | Statistical significance not reported | |
| Number of therapeutic abortions (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy + infancy and comparison (Elmira) | 205 mothers | Adjusted mean = 0.05 | Adjusted mean = 0.04 | Mean difference = 0.01 | Not available | Not statistically significant, p ≥ 0.05 | Statistical significance reported on authors’ calculations of the log-incidence difference.
|
| Number of therapeutic abortions (0–46 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
46 months, postpartum | Nurse visited during pregnancy and comparison (Elmira) | 194 mothers | Adjusted mean = 0.05 | Adjusted mean = 0.04 | Mean difference = 0.01 | Not available | Statistical significance not reported |
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
|---|---|---|---|---|---|---|---|---|---|
| Alcohol or other drug use | FavorableUnfavorable or ambiguousNo Effect |
12-year follow-up | Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 594 mothers | %(adjusted) = 10.00 | Adjusted mean % = 10.00 | OR = 0.91 | HomVEE calculated = -0.05 | Not statistically significant, p ≥ 0.05 |
| Cumulative subsequent births | FavorableUnfavorable or ambiguousNo Effect |
0 to 12 years | Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 594 mothers | Adjusted mean = 1.07 | Adjusted mean = 1.15 | Mean difference = -0.08 | HomVEE calculated = -1.69 | Not statistically significant, p ≥ 0.05 |
| Cumulative subsequent births | FavorableUnfavorable or ambiguousNo Effect |
10 to 12 years | Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 594 mothers | Adjusted mean = 1.80 | Adjusted mean = 1.83 | Mean difference = -0.03 | HomVEE calculated = -0.42 | Not statistically significant, p ≥ 0.05 |
| Pearlin Mastery Scale | FavorableUnfavorable or ambiguousNo Effect |
12-year follow-up | Nurse visited during pregnancy + infancy and development screening comparison (Memphis) | 594 mothers | Adjusted mean = 101.07 | Adjusted mean = 99.56 | Mean difference = 1.51 | HomVEE calculated = 2.80 | Not statistically significant, p ≥ 0.05 |
| Pearlin Mastery Scale | FavorableUnfavorable or ambiguousNo Effect |
6 months to 12 years | Nurse visited during pregnancy + infancy and development screening comparison (Memphis) | 594 mothers | Adjusted mean = 101.04 | Adjusted mean = 99.60 | Mean difference = 1.44 | HomVEE calculated = 4.30 | Statistically significant, p < .05 |
| Role impairment due to alcohol or drug use | FavorableUnfavorable or ambiguousNo Effect |
12-year follow-up | Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 594 mothers | %(adjusted) = 0.00 | Adjusted mean % = 3.00 | Difference = -0.03 | Not available | Statistically significant, p < .05 |
| Symptoms of psychological distress (borderline/clinical vs. normal) | FavorableUnfavorable or ambiguousNo Effect |
12-year follow-up | Nurse visited during pregnancy and infancy and development screening comparison (Memphis) | 594 mothers | %(adjusted) = 18.00 | Adjusted mean % = 17.00 | OR = 1.09 | HomVEE calculated = 0.05 | Not statistically significant, p ≥ 0.05 |
171
Nurse-Family Partnership (NFP)®
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| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
Beck Anxiety Screening Inventory, clinical or borderline threshold |
FavorableUnfavorable or ambiguousNo Effect |
18 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
617 mothers | Adjusted proportion = 0.09 | Adjusted proportion = 0.10 | Odds ratio = 0.94 | HomVEE calculated = -0.04 | Not statistically significant, p= 0.82 |
Negative effect is favorable to the intervention. HomVEE calculated the effect size based on the study-reported odds ratio. |
Beck Depression Screening Inventory, Maternal depression, clinical or borderline threshold |
FavorableUnfavorable or ambiguousNo Effect |
18 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
617 mothers | Adjusted proportion = 0.09 | Adjusted proportion = 0.08 | Odds ratio = 1.12 | HomVEE calculated = 0.07 | Not statistically significant, p= 0.72 |
Negative effect is favorable to the intervention. HomVEE calculated the effect size based on the study-reported odds ratio. |
Drug Use Screening Inventory (DUSI), current substance use |
FavorableUnfavorable or ambiguousNo Effect |
18 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
617 mothers | Adjusted proportion = 0.24 | Adjusted proportion = 0.27 | Odds ratio = 0.87 | HomVEE calculated = -0.08 | Not statistically significant, p= 0.49 |
Negative effect is favorable to the intervention. HomVEE calculated the effect size based on the study-reported odds ratio. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
1 year |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
694 mothers | Adjusted mean = 0.00 | Adjusted mean = 0.04 | Mean difference = -0.04 | HomVEE calculated = -0.30 | Statistically significant, p = 0.00 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
10 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
645 mothers | Adjusted mean = 1.68 | Adjusted mean = 1.74 | Mean difference = -0.06 | HomVEE calculated = -0.05 | Not statistically significant, p = 0.58 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
11 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
643 mothers | Adjusted mean = 1.78 | Adjusted mean = 1.85 | Mean difference = -0.07 | HomVEE calculated = -0.05 | Not statistically significant, p = 0.54 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
12 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
643 mothers | Adjusted mean = 1.87 | Adjusted mean = 1.93 | Mean difference = -0.06 | HomVEE calculated = -0.04 | Not statistically significant, p = 0.62 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
13 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
629 mothers | Adjusted mean = 1.94 | Adjusted mean = 2.00 | Mean difference = -0.06 | HomVEE calculated = -0.04 | Not statistically significant, p = 0.64 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
14 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
618 mothers | Adjusted mean = 1.99 | Adjusted mean = 2.05 | Mean difference = -0.06 | HomVEE calculated = -0.04 | Not statistically significant, p = 0.65 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
15 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
618 mothers | Adjusted mean = 2.03 | Adjusted mean = 2.09 | Mean difference = -0.06 | HomVEE calculated = -0.04 | Not statistically significant, p = 0.66 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
16 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
618 mothers | Adjusted mean = 2.07 | Adjusted mean = 2.13 | Mean difference = -0.06 | HomVEE calculated = -0.04 | Not statistically significant, p = 0.67 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
17 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
618 mothers | Adjusted mean = 2.09 | Adjusted mean = 2.17 | Mean difference = -0.08 | HomVEE calculated = -0.05 | Not statistically significant, p = 0.57 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
18 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
574 mothers | Adjusted mean = 2.12 | Adjusted mean = 2.21 | Mean difference = -0.09 | HomVEE calculated = -0.05 | Not statistically significant, p = 0.54 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
2 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
686 mothers | Adjusted mean = 0.15 | Adjusted mean = 0.24 | Mean difference = -0.09 | HomVEE calculated = -0.25 | Statistically significant, p = 0.00 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
3 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
681 mothers | Adjusted mean = 0.39 | Adjusted mean = 0.53 | Mean difference = -0.14 | HomVEE calculated = -0.25 | Statistically significant, p = 0.00 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
4 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
681 mothers | Adjusted mean = 0.62 | Adjusted mean = 0.78 | Mean difference = -0.16 | HomVEE calculated = -0.24 | Statistically significant, p = 0.00 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
5 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
670 mothers | Adjusted mean = 0.83 | Adjusted mean = 1.00 | Mean difference = -0.17 | HomVEE calculated = -0.22 | Statistically significant, p = 0.01 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
6 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
668 mothers | Adjusted mean = 1.05 | Adjusted mean = 1.20 | Mean difference = -0.15 | HomVEE calculated = -0.17 | Statistically significant, p < 0.05 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
7 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
660 mothers | Adjusted mean = 1.23 | Adjusted mean = 1.38 | Mean difference = -0.15 | HomVEE calculated = -0.15 | Not statistically significant, p = 0.08 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
8 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
658 mothers | Adjusted mean = 1.41 | Adjusted mean = 1.54 | Mean difference = -0.13 | HomVEE calculated = -0.12 | Not statistically significant, p = 0.17 |
Statistical significance is based on HomVEE calculations. |
Mothers' subsequent births |
FavorableUnfavorable or ambiguousNo Effect |
9 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
658 mothers | Adjusted mean = 1.55 | Adjusted mean = 1.65 | Mean difference = -0.10 | HomVEE calculated = -0.08 | Not statistically significant, p = 0.32 |
Statistical significance is based on HomVEE calculations. |
Pearlin Mastery Scale |
FavorableUnfavorable or ambiguousNo Effect |
12 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
582 mothers | Unadjusted mean = 100.59 | Unadjusted mean = 99.71 | Mean difference = 0.88 | HomVEE calculated = 0.09 | Not statistically significant, p = 0.32 |
Statistical significance is based on HomVEE calculations. |
Pearlin Mastery Scale |
FavorableUnfavorable or ambiguousNo Effect |
18 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
616 mothers | Adjusted proportion = 100.74 | Adjusted proportion = 99.69 | Mean difference = 1.05 | Study reported = 1.98 | Not statistically significant, p= 0.19 |
|
Pearlin Mastery Scale |
FavorableUnfavorable or ambiguousNo Effect |
2 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
670 mothers | Unadjusted mean = 101.28 | Unadjusted mean = 99.41 | Mean difference = 1.87 | HomVEE calculated = 0.19 | Statistically significant, p = 0.03 |
Statistical significance is based on HomVEE calculations. |
Pearlin Mastery Scale |
FavorableUnfavorable or ambiguousNo Effect |
36th week of pregnancy |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
657 mothers | Unadjusted mean = 101.00 | Unadjusted mean = 99.56 | Mean difference = 1.44 | HomVEE calculated = 0.14 | Not statistically significant, p = 0.09 |
Statistical significance is based on HomVEE calculations. |
Pearlin Mastery Scale |
FavorableUnfavorable or ambiguousNo Effect |
6 months |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
666 mothers | Unadjusted mean = 100.47 | Unadjusted mean = 99.82 | Mean difference = 0.65 | HomVEE calculated = 0.07 | Not statistically significant, p = 0.44 |
Statistical significance is based on HomVEE calculations. |
Pearlin Mastery Scale |
FavorableUnfavorable or ambiguousNo Effect |
6 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
635 mothers | Unadjusted mean = 100.26 | Unadjusted mean = 99.87 | Mean difference = 0.39 | HomVEE calculated = 0.04 | Not statistically significant, p = 0.65 |
Statistical significance is based on HomVEE calculations. |
Pearlin Mastery Scale |
FavorableUnfavorable or ambiguousNo Effect |
9 years |
NFP vs. Resource referral RCT, Memphis TN, 1990-2015, full sample |
625 mothers | Unadjusted mean = 100.37 | Unadjusted mean = 99.83 | Mean difference = 0.54 | HomVEE calculated = 0.05 | Not statistically significant, p = 0.53 |
Statistical significance is based on HomVEE calculations. |
171
Nurse-Family Partnership (NFP)®
Show findings details
| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| MHI | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | Adjusted mean = 100.18 | Adjusted mean = 99.92 | Mean difference = 0.26 | Study reported = 0.03 | Not statistically significant, p = 0.76 |
|
| Behavioral problems attributable to substance abuse | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | % (adjusted) = 4.00 | Adjusted mean % = 4.00 | OR = 0.94 | HomVEE calculated = -0.03 | Not statistically significant, p = 0.88 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Currently uses marijuana | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | % (adjusted) = 5.00 | Adjusted mean % = 3.00 | OR = 1.37 | HomVEE calculated = 0.19 | Not statistically significant, p = 0.47 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Moderate/heavy drinker (= 3 drinks = 3 times per month) | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | % (adjusted) = 5.00 | Adjusted mean % = 3.00 | OR = 2.03 | HomVEE calculated = 0.44 | Not statistically significant, p = 0.11 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Months between births of first and second children | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | Adjusted mean = 34.38 | Adjusted mean = 30.23 | Mean difference = 4.15 | Study reported = 0.26 | Statistically significant, p = 0.01 |
|
| Number of subsequent children (birth to 72 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | Adjusted mean = 1.08 | Adjusted mean = 1.28 | Mean difference = -0.20 | Study reported = -0.22 | Statistically significant, p = 0.01 |
|
| Number of subsequent pregnancies (birth to 72 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | Adjusted mean = 1.16 | Adjusted mean = 1.38 | Mean difference = -0.22 | Study reported = -0.22 | Statistically significant, p = 0.01 |
|
| Pearlin Mastery Scale | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | Adjusted mean = 100.46 | Adjusted mean = 99.79 | Mean difference = 0.67 | Study reported = 0.07 | Not statistically significant, p = 0.43 |
|
| Subsequent abortion (rate per subsequent pregnancy) | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | % (adjusted) = 4.00 | Adjusted mean % = 5.00 | OR = 0.70 | HomVEE calculated = -0.23 | Not statistically significant, p = 0.42 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Subsequent miscarriage (rate per subsequent pregnancy) | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | % (adjusted) = 3.00 | Adjusted mean % = 5.00 | OR = 0.75 | HomVEE calculated = -0.27 | Not statistically significant, p = 0.50 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
171
Nurse-Family Partnership (NFP)®
Show findings details
| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| Cumulative subsequent live birth per year (6–9 years postpartum) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy during infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 1.40 | Adjusted mean = 1.53 | Mean difference = -0.13 | Study reported = -0.16 | Not statistically significant, p = 0.17 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Cumulative subsequent live births per year (0–9 yr postpartum) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 0.81 | Adjusted mean = 0.93 | Mean difference = -0.12 | Study reported = -0.14 | Statistically significant, p < 0.05 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Maternal depression (CES-D) (9 years postpartum) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 1.71 | Adjusted mean = 1.72 | Mean difference = 0.01 | Study reported = -0.01 | Not statistically significant, p = 0.87 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Number of months between birth of first and second child | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 40.73 | Adjusted mean = 34.09 | Mean difference = 6.64 | Study reported = 0.29 | Statistically significant, p < 0.01 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Number of subsequent abortions | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 0.14 | Adjusted mean = 0.20 | Mean difference = -0.06 | Not available | Not statistically significant, p = 0.15 |
Statistical significance reported on authors’ calculation of incidence ratio.
|
| Number of subsequent miscarriages (0–9 years postpartum) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 0.24 | Adjusted mean = 0.24 | Mean difference = 0.00 | Not available | Not statistically significant, p = 1.00 |
Statistical significance reported on authors’ calculation of incidence ratio.
|
| Number of substances used (moderate/heavy alcohol, marijuana, cocaine) since last interview | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 0.10 | Adjusted mean = 0.17 | Mean difference = -0.07 | Not available | Not statistically significant, p = 0.08 |
Statistical significance reported on authors’ calculation of incidence ratio.
|
| Pearlin Mastery Scale (9 years postpartum) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 100.79 | Adjusted mean = 99.75 | Mean difference = 1.04 | Study reported = 0.10 | Not statistically significant, p = 0.20 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Pearlin Mastery Scale (6 months–9 years postpartum) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 101.00 | Adjusted mean = 99.50 | Mean difference = 1.53 | Study reported = 0.15 | Statistically significant, p < 0.01 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
| Subsequent still birth (0–9 years postpartum), percentage | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | % (adjusted) = 1.00 | Adjusted mean % = 2.00 | Mean difference = -1.00 | Study reported = 1.00 | Not statistically significant, p = 0.36 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
171
Nurse-Family Partnership (NFP)®
Show findings details
| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
|---|---|---|---|---|---|---|---|---|---|
| Subsequent birth (24 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
24 months | Nurse home visitor and comparison (Denver) | 436 mothers | % (adjusted) = 12.00 | Adjusted mean % = 19.00 | OR = 0.58 | HomVEE calculated = -0.33 | Statistically significant, p ≤ 0.05 |
| Subsequent pregnancy (24 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
24 months | Nurse home visitor and comparison (Denver) | 436 mothers | % (adjusted) = 29.00 | Adjusted mean % = 41.00 | OR = 0.60 | HomVEE calculated = -0.32 | Statistically significant, p ≤ 0.05 |
171
Nurse-Family Partnership (NFP)®
Show findings details
| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
|---|---|---|---|---|---|---|---|---|---|
| MHI | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | Adjusted mean = 99.82 | Adjusted mean = 99.16 | Mean difference = 0.66 | Study reported = 0.04 | Not statistically significant, p = 0.49 |
| Behavioral problems attributable to substance use | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | = 0.15 | = 0.12 | OR = 1.27 | HomVEE calculated = 0.15 | Not statistically significant, p = 0.41 |
| Currently using marijuana | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | = 0.08 | = 0.09 | OR = 0.86 | HomVEE calculated = -0.09 | Not statistically significant, p = 0.67 |
| Moderate/heavy drinker (= 3 drinks, = 3 times in 14 days) | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | = 0.04 | = 0.04 | OR = 1.09 | HomVEE calculated = 0.06 | Not statistically significant, p = 0.84 |
| Months between births of first and second children | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | Adjusted mean = 24.51 | Adjusted mean = 20.39 | Mean difference = 4.12 | Study reported = 0.32 | Statistically significant, p = 0.01 |
| Number of subsequent live births | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | Adjusted mean = 0.48 | Adjusted mean = 0.57 | Mean difference = -0.09 | Study reported = -0.13 | Not statistically significant, p = 0.18 |
| Number of subsequent pregnancies | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | Adjusted mean = 0.85 | Adjusted mean = 0.88 | Mean difference = -0.03 | Study reported = -0.04 | Not statistically significant, p = 0.72 |
| Pearlin Mastery Scale | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | Adjusted mean = 99.41 | Adjusted mean = 99.31 | Mean difference = 0.10 | Study reported = 0.12 | Not statistically significant, p = 0.91 |
| Subsequent abortion | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | = 0.05 | = 0.05 | OR = 0.94 | HomVEE calculated = -0.04 | Not statistically significant, p = 0.89 |
| Subsequent miscarriage | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | = 0.09 | = 0.12 | OR = 0.73 | HomVEE calculated = -0.19 | Not statistically significant, p = 0.31 |
260
NFP with Paraprofessional Home Visitors
Show findings details
| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| Subsequent birth (24 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
24 months | Paraprofessional home visitor and comparison (Denver) | 417 mothers | % (adjusted) = 13.00 | Adjusted mean % = 19.00 | OR = 0.63 | HomVEE calculated = -0.27 | Not statistically significant, p > 0.05 | Authors report the difference in this outcome to be statistically significant, p < 0.10, which is greater than the acceptable alpha for this review (α = 0.05).
|
| Subsequent pregnancy (24 months postpartum) | FavorableUnfavorable or ambiguousNo Effect |
24 months | Paraprofessional home visitor and comparison (Denver) | 417 mothers | % (adjusted) = 33.00 | Adjusted mean % = 41.00 | OR = 0.70 | HomVEE calculated = -0.21 | Not statistically significant, p > 0.05 | Authors report the difference in this outcome to be statistically significant, p < 0.10, which is greater than the acceptable alpha for this review (α = 0.05).
|
| Use of emergency services | FavorableUnfavorable or ambiguousNo Effect |
36 weeks (prenatal) | Paraprofessional home visitor and comparison (Denver) | 344 mothers | % (adjusted) = 9.00 | Adjusted mean % = 9.00 | OR = 1.01 | HomVEE calculated = 0.00 | Not statistically significant, p > 0.05 |
|
| Use of preventative services | FavorableUnfavorable or ambiguousNo Effect |
36 weeks (prenatal) | Paraprofessional home visitor and comparison (Denver) | 344 mothers | Adjusted mean = 0.67 | Adjusted mean = 0.69 | Mean difference = -0.02 | Not available | Not statistically significant, p > 0.05 |
Findings rated moderate
Nurse-Family Partnership (NFP)®
Show findings details
| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| Alcohol impairment score | FavorableUnfavorable or ambiguousNo Effect |
15 years | Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample | 300 mothers | Unadjusted mean = 0.35 | Unadjusted mean = 0.37 | MD = -0.02 | HomVEE calculated = -0.02 | Not statistically significant, p = 0.87 | Statistical significance is based on HomVEE calculations. |
| Substance use - # cigarettes smoked per day | FavorableUnfavorable or ambiguousNo Effect |
15 years | Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample | 300 mothers | Unadjusted mean = 8.32 | Unadjusted mean = 10.56 | MD = -2.24 | HomVEE calculated = -0.21 | Not statistically significant, p = 0.11 | Statistical significance is based on HomVEE calculations. |
| Substance use - binge drinking: # days had 5+ drinks in the past year | FavorableUnfavorable or ambiguousNo Effect |
15 years | Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample | 300 mothers | Unadjusted mean = 11.70 | Unadjusted mean = 9.27 | MD = 2.43 | HomVEE calculated = 0.06 | Not statistically significant, p = 0.65 | Statistical significance is based on HomVEE calculations. |
Nurse-Family Partnership (NFP)®
Show findings details
| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
|---|---|---|---|---|---|---|---|---|---|
| Use of emergency services | FavorableUnfavorable or ambiguousNo Effect |
36 weeks (prenatal) | Nurse home visitor and comparison (Denver) | 353 mothers | % (adjusted) = 6.00 | Adjusted mean % = 9.00 | OR = 0.64 | HomVEE calculated = -0.27 | Not statistically significant, p > 0.05 |
| Use of preventative services | FavorableUnfavorable or ambiguousNo Effect |
36 weeks (prenatal) | Nurse home visitor and comparison (Denver) | 353 mothers | Adjusted mean = 0.80 | Adjusted mean = 0.69 | Mean difference = 0.11 | HomVEE calculated = 0.09 | Not statistically significant, p > 0.05 |
Nurse-Family Partnership (NFP)®
Show findings details
| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
| 21 year maternal mortality rate - all causes (Nurse home visits during pregnancy and infancy vs. transport to prenatal appointment comparison) | FavorableUnfavorable or ambiguousNo Effect |
21 years | Nurse home visits during pregnancy and infancy vs. transport to prenatal appointment comparison (Memphis) | 1138 mother/child dyads | Unadjusted mean = 0.01 | Unadjusted mean = 0.04 | Mean difference = -0.03 | HomVEE calculated = -0.69 | Statistically significant, p = 0.01 | Negative value is favorable to the intervention.
|
| 21 year maternal mortality rate - all causes (Nurse home visits during pregnancy and infancy vs. transport to prenatal appointment comparison) | FavorableUnfavorable or ambiguousNo Effect |
21 years | Nurse home visits during pregnancy and infancy vs. transport to prenatal appointment comparison (Memphis) | 1138 mother/child dyads | Unadjusted mean = 0.01 | Unadjusted mean = 0.04 | Mean difference = -0.03 | HomVEE calculated = -0.69 | Statistically significant, p = 0.01 | Negative value is favorable to the intervention.
|
| 21 year maternal mortality rate - all causes (Nurse home visits during pregnancy plus 2 postpartum visits vs. transport to prenatal appointment comparison) | FavorableUnfavorable or ambiguousNo Effect |
21 years | Nurse home visits during pregnancy plus 2 postpartum visits vs. transport to prenatal appointment comparison (Memphis) | 910 mother/child dyads | Unadjusted mean = 0.00 | Unadjusted mean = 0.04 | Mean difference = -0.04 | HomVEE calculated = -1.41 | Statistically significant, p = 0.01 | Negative value is favorable to the intervention.
|
| 21 year maternal mortality rate - external cause (Nurse home visits during pregnancy and infancy vs. transport to prenatal appointment comparison) | FavorableUnfavorable or ambiguousNo Effect |
21 years | Nurse home visits during pregnancy and infancy vs. transport to prenatal appointment comparison (Memphis) | 1138 mother/child dyads | Unadjusted mean = 0.00 | Unadjusted mean = 0.02 | Mean difference = -0.01 | HomVEE calculated = -1.22 | Statistically significant, p = 0.02 | Negative value is favorable to the intervention.
|
| 21 year maternal mortality rate - external cause (Nurse home visits during pregnancy and infancy vs. transport to prenatal appointment comparison) | FavorableUnfavorable or ambiguousNo Effect |
21 years | Nurse home visits during pregnancy and infancy vs. transport to prenatal appointment comparison (Memphis) | 1138 mother/child dyads | Unadjusted mean = 0.00 | Unadjusted mean = 0.02 | Mean difference = -0.01 | HomVEE calculated = -1.22 | Statistically significant, p = 0.02 | Negative value is favorable to the intervention.
|
| 21 year maternal mortality rate - external cause (Nurse home visits during pregnancy plus 2 postpartum visits vs. transport to prenatal appointment comparison) | FavorableUnfavorable or ambiguousNo Effect |
21 years | Nurse home visits during pregnancy plus 2 postpartum visits vs. transport to prenatal appointment comparison (Memphis) | 910 mother/child dyads | Unadjusted mean = 0.00 | Unadjusted mean = 0.02 | Mean difference = -0.02 | Not available | Not statistically significant, p = 0.05 | Negative value is favorable to the intervention.
|
NFP with Paraprofessional Home Visitors
Show findings details
| Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
|---|---|---|---|---|---|---|---|---|---|
| MHI | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | Adjusted mean = 101.20 | Adjusted mean = 99.16 | Mean difference = 0.66 | Study reported = -0.03 | Statistically significant, p = 0.03 |
| Behavioral problems attributable to substance use | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | = 0.10 | = 0.12 | OR = 0.82 | HomVEE calculated = -0.12 | Not statistically significant, p = 0.52 |
| Currently using marijuana | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison, (Denver) | 431 mothers | = 0.09 | = 0.09 | OR = 0.94 | HomVEE calculated = -0.04 | Not statistically significant, p = 0.87 |
| Moderate/heavy drinker (= 3 drinks, = 3 times in 14 days) | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | = 0.03 | = 0.04 | OR = 0.74 | HomVEE calculated = -0.21 | Not statistically significant, p = 0.54 |
| Months between births of first and second children | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | Adjusted mean = 22.20 | Adjusted mean = 20.39 | Mean difference = 1.81 | Study reported = 0.14 | Not statistically significant, p = 0.27 |
| Number of subsequent live births | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | Adjusted mean = 0.53 | Adjusted mean = 0.57 | Mean difference = -0.04 | Study reported = -0.06 | Not statistically significant, p = 0.57 |
| Number of subsequent pregnancies | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | Adjusted mean = 0.88 | Adjusted mean = 0.88 | Mean difference = 0.00 | Study reported = 0.00 | Not statistically significant, p = 1.00 |
| Pearlin Mastery Scale | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | Adjusted mean = 101.20 | Adjusted mean = 99.31 | Mean difference = 1.94 | Study reported = 0.20 | Statistically significant, p = 0.03 |
| Subsequent abortion | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | = 0.06 | = 0.05 | OR = 1.19 | HomVEE calculated = 0.10 | Not statistically significant, p = 0.67 |
| Subsequent miscarriage | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | = 0.07 | = 0.12 | OR = 0.50 | HomVEE calculated = -0.42 | Statistically significant, p = 0.04 |